01734nam a22002657a 4500001000700000003000900007005001700016008004100033040001300074041000800087082001700095100004300112245014700155260004300302300003000345504005100375520075300426650003101179650005101210650003101261700003901292942000701331999001701338952011301355PHD430IN-BhIIT20261021184445.0261021b        |||||||| |||| 00| 0 eng d  aIN-BhIIT  aeng  a572.8bSEN/D  aSenapati, Swayamshree,eauthor.928761  aDecoding gene regulation through genome architecture using molecular simulations /cSwayamshree Senapati ; under the guidance of Hemant Kumar.  aBhubaneswar :bIIT Bhubaneswar,c2026.  axxxi, 196 pages ;c30 cm.  aIncludes bibliographical references and index.  aDecoding Gene Regulation through Genome Architecture Using Molecular Simulations: This thesis explores how the three-dimensional organization of the genome influences gene regulation and the control of gene expression. Using molecular simulation techniques, the research investigates structural features and molecular interactions involving DNA, regulatory elements, and associated molecules that contribute to gene activity. It aims to improve understanding of the relationship between genome architecture and regulatory mechanisms at the molecular level. The study contributes to computational and molecular biology by examining how the organization and dynamics of genomic structures help explain the complex processes governing gene expression.  aGenomesxStructure.928762  aMolecular dynamicsxComputer simulation.96890  aMolecular modeling.928763  aKumar, Hemant,esupervisor.921680  cTH  c15810d15810  001040708SBSaCLIITBBSbCLIITBBSd2026-10-01l0o572.8 SEN/DpPHD430r2026-10-21 18:45:13w2026-10-21yTH