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  <titleInfo>
    <title>Decoding gene regulation through genome architecture using molecular simulations</title>
  </titleInfo>
  <name type="personal">
    <namePart>Senapati, Swayamshree</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
    <role>
      <roleTerm type="text">author.</roleTerm>
    </role>
  </name>
  <name type="personal">
    <namePart>Kumar, Hemant</namePart>
    <role>
      <roleTerm type="text">supervisor.</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <originInfo>
    <place>
      <placeTerm type="text">Bhubaneswar</placeTerm>
    </place>
    <publisher>IIT Bhubaneswar</publisher>
    <dateIssued>2026</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xxxi, 196 pages ; 30 cm.</extent>
  </physicalDescription>
  <abstract>Decoding Gene Regulation through Genome Architecture Using Molecular Simulations: This thesis explores how the three-dimensional organization of the genome influences gene regulation and the control of gene expression. Using molecular simulation techniques, the research investigates structural features and molecular interactions involving DNA, regulatory elements, and associated molecules that contribute to gene activity. It aims to improve understanding of the relationship between genome architecture and regulatory mechanisms at the molecular level. The study contributes to computational and molecular biology by examining how the organization and dynamics of genomic structures help explain the complex processes governing gene expression.</abstract>
  <note type="statement of responsibility">Swayamshree Senapati ; under the guidance of Hemant Kumar.</note>
  <note>Includes bibliographical references and index.</note>
  <subject>
    <topic>Genomes</topic>
    <topic>Structure</topic>
  </subject>
  <subject>
    <topic>Molecular dynamics</topic>
    <topic>Computer simulation</topic>
  </subject>
  <subject>
    <topic>Molecular modeling</topic>
  </subject>
  <classification authority="ddc">572.8 SEN/D</classification>
  <recordInfo>
    <recordContentSource authority="marcorg">IN-BhIIT</recordContentSource>
    <recordCreationDate encoding="marc">261021</recordCreationDate>
    <recordChangeDate encoding="iso8601">20261021184445.0</recordChangeDate>
    <recordIdentifier source="IN-BhIIT">PHD430</recordIdentifier>
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